Akash Gupta is a PhD student at Oklahoma State University in Industrial Engineering and Management. After completing his Masters in Control Systems from Indian Institute of Technology (BHU) - Varanasi, he joined Indian Institute of Management - Ahmedabad as a Research Associate under the Production and Quantitative Methods Area. His research work, published in elite Journals, inspired him for the higher studies and brought him to OSU. Currently, his research orients towards Healthcare Analytics. He has Health Insurance Portability and Accountability Act (HIPAA) certification, and is managing 63 million patient (1.3 Crore) clinical dataset donated to OSU by Cerner Corporation. More specifically, he endeavors to improve the sepsis care by developing an effective diagnostic criteria. Along with his technical expertise, he also enjoys learning Japanese language and have earned JLPT-N4 certificate.
Sepsis, traditionally known as the systemic response to infection, is “a life-threatening organ dysfunction caused by a dysregulated host response to an infection” (Singer et al., 2016). Sepsis develops into septic shock when body organs start behaving abnormally. According to the new definition, the organ dysfunction is identified using the increment of 2 or more in the Sequential [Sepsis-related] Organ Failure Assessment (SOFA) score. Due to technological advancements in pathobiology and epidemiology of sepsis, sepsis definition and diagnostic procedures have been revised to control the high mortality and growing incidence.
The incidences of sepsis are growing rapidly in United States. According to Centers for Disease Control and Prevention, the number of admissions to intensive care units (ICU) due to sepsis increased 83.75% from 621,000 in 2000 to 1,141,000 in 2008 (Hall et al., 2011). A recent word-wide study showed that for high income countries the incidence of sepsis and severe sepsis were 437 and 270, respectively, per 100,000 person per year in last decade (2005 to 2015) (Fleischmann et al., 2016). Sepsis is considered as one of the most expensive diseases among payers (e.g., insurance companies), with annual cost of treatment of severe sepsis in the United States of approximately $15.4 billion in 2003 that is increased by 57% to $24.3 billion in 2007 (Lagu et al., 2012). It is a leading cause of death for patients admitted to ICUs, with mortality rates ranging from about 20-45% depending on sepsis severity (Rangel-Frausto et al., 1995). Another study found that the admission to hospital due to sepsis consisted only 11.3-11.5% of total admission to hospital while in-hospital mortality among the sepsis patients was very high about 36.9-55% (Liu et al., 2014).
Industrial Engineering & Management
Oklahoma State University
Stillwater, OK, USA-74078
Office Address: 221, ATRC